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Table 2 Cell cycle distribution and percentage of apoptosis for the BAPTA-AM→A23187-treated, A23187-treated, and untreated cells (x ± s) %

From: Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells

Groups

Cell cycle distribution

Percentage of apoptosis

 

G0/G1

S

G2/M

 

BAPTA-AM (40 μM) → A23187 – treated

42.00 ± 1.33

43.50 ± 2.17

14.50 ± 1.56

56.5 ± 2.13

A23187-treated (2 μM)

76.00 ± 1.24

21.40 ± 3.03

2.60 ± 2.14

7.18 ± 1.03

untreated

58.90 ± 1.48

39.00 ± 1.27

2.10 ± 1.15

27.8 ± 1.45

  1. Compared with control (untreated) group, P < 0.05.