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Table 2 Cell cycle distribution and percentage of apoptosis for the BAPTA-AM→A23187-treated, A23187-treated, and untreated cells (x ± s) %

From: Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells

Groups Cell cycle distribution Percentage of apoptosis
  G0/G1 S G2/M  
BAPTA-AM (40 μM) → A23187 – treated 42.00 ± 1.33 43.50 ± 2.17 14.50 ± 1.56 56.5 ± 2.13
A23187-treated (2 μM) 76.00 ± 1.24 21.40 ± 3.03 2.60 ± 2.14 7.18 ± 1.03
untreated 58.90 ± 1.48 39.00 ± 1.27 2.10 ± 1.15 27.8 ± 1.45
  1. Compared with control (untreated) group, P < 0.05.