FBP1 and FBP3 expression in normal kidney and renal cancer. A) Normal renal tissue shows a moderate FPB1 expression in epithelia of distal tubules, whereas proximal tubules show no immunoreactivity. Podocytes and endothelia of the Bowman capsule are also FBP1 positive (20×). B) ccRCC lacking FBP1 expression (20×).C) ccRCC with moderate FBP1 immunoreactivity (20×). D) Example of a strong FBP1 expression in a ccRCC, 20×. E) Normal renal tissue with a strong FBP3 expression in epithelia of proximal and distal tubules (40×). F) FBP3-negative ccRCC (20×). G) FBP3 positive papillary RCC (20×). H) ccRCC with strong FPB3 expression (20×).