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Table 4 Age-Adjusted Incidence Rate and Relative Risk of Cancer by Smoking Status and Leisure-time Physical activitya

From: Dietary preference, physical activity, and cancer risk in men: national health insurance corporation study

Cancer site

Never/Former Smoker

Current Smoker

 

Low

Moderate-High

Low

Moderate-High

All

(n = 2,839)

(n = 1,995)

(n = 5,494)

(n = 3,257)

Age aIRb

478.2

433.6

627.5

570.7

Age aRR (95% CI)

1.00

0.91 (0.86 – 0.96)

1.00

0.91 (0.87 – 0.95)

Multivariate (95% CI)c

1.00

0.91 (0.86 – 0.97)

1.00

0.92 (0.88 – 0.96)

Head and neck

(n = 125)

(n = 114)

(n = 280)

(n = 157)

Age aIRb

21.7

25.4

32.3

27.8

Age aRR (95% CI)

1.00

1.17 (0.91 – 1.51)

1.00

0.86 (0.71 – 1.05)

Multivariate (95% CI)c

1.00

1.17 (0.91 – 1.51)

1.00

0.87 (0.71 – 1.05)

Esophagus

(n = 37)

(n = 26)

(n = 152)

(n = 78)

Age aIRb

5.2

2.5

15.3

12.1

Age aRR (95% CI)

1.00

0.91 (0.55 – 1.50)

1.00

0.79 (0.60 – 1.04)

Multivariate (95% CI)c

1.00

0.89 (0.54 – 1.47)

1.00

0.82 (0.62 – 1.08)

Stomach

(n = 743)

(n = 505)

(n = 1449)

(n = 886)

Age aIRb

123.6

108.5

165.1

154.7

Age aRR (95% CI)

1.00

0.88 (0.78 – 0.98)

1.00

0.94 (0.86 – 1.02)

Multivariate (95% CI)c

1.00

0.88 (0.79 – 0.99)

1.00

0.94 (0.86 – 1.02)

Lung

(n = 220)

(n = 139)

(n = 788)

(n = 412)

Age aIRb

36.8

30.1

87.9

71.0

Age aRR (95% CI)

1.00

0.82 (0.66 – 1.01)

1.00

0.81 (0.72 – 0.91)

Multivariate (95% CI)c

1.00

0.82 (0.66 – 1.02)

1.00

0.83 (0.73 – 0.93)

Colorectum

(n = 462)

(n = 339)

(n = 600)

(n = 401)

Age aIRb

78.4

74.3

70.3

72.3

Age aRR (95% CI)

1.00

0.95 (0.82 – 1.09)

1.00

1.03 (0.91 – 1.17)

Multivariate (95% CI)c

1.00

0.93 (0.81 – 1.07)

1.00

1.02 (0.90 – 1.16)

Liver

(n = 588)

(n = 375)

(n = 1051)

(n = 616)

Age aIRb

94.7

77.6

110.9

99.0

Age aRR (95% CI)

1.00

0.82 (0.72 – 0.93)

1.00

0.89 (0.81 – 0.99)

Multivariate (95% CI)c

1.00

0.86 (0.75 – 0.98)

1.00

0.91 (0.82 – 1.00)

Gallbladder

(n = 78)

(n = 51)

(n = 133)

(n = 71)

Age aIRb

13.6

11.5

15.5

12.7

Age aRR (95% CI)

1.00

0.84 (0.59 – 1.20)

1.00

0.82 (0.62 – 1.10)

Multivariate (95% CI)c

1.00

0.85 (0.60 – 1.21)

1.00

0.82 (0.61 – 1.09)

Pancreas

(n = 67)

(n = 51)

(n = 134)

(n = 89)

Age aIRb

10.1

10.0

15.6

16.0

Age aRR (95% CI)

1.00

0.99 (0.68 – 1.42)

1.00

1.02 (0.78 – 1.34)

Multivariate (95% CI)c

1.00

0.96 (0.67 – 1.39)

1.00

1.02 (0.78 – 1.34)

Kidney

(n = 84)

(n = 64)

(n = 144)

(n = 97)

Age aIRb

14.2

13.9

16.5

17.0

Age aRR (95% CI)

1.00

0.98 (0.71 – 1.36)

1.00

1.03 (0.80 – 1.33)

Multivariate (95% CI)c

1.00

0.94 (0.68 – 1.30)

1.00

1.02 (0.78 – 1.32)

Bladder

(n = 68)

(n = 60)

(n = 177)

(n = 103)

Age aIRb

11.2

12.8

20.4

18.3

Age aRR (95% CI)

1.00

1.14 (0.81 – 1.62)

1.00

0.89 (0.70 – 1.14)

Multivariate (95% CI)c

1.00

1.15 (0.81 – 1.63)

1.00

0.89 (0.69 – 1.13)

Prostate

(n = 85)

(n = 57)

(n = 97)

(n = 55)

Age aIRb

11.9

10.4

9.8

8.7

Age aRR (95% CI)

1.00

0.88 (0.63 – 1.23)

1.00

0.89 (0.64 – 1.24)

Multivariate (95% CI)c

1.00

0.89 (0.63 – 1.24)

1.00

0.89 (0.64 – 1.24)

  1. The number in the parenthesis means the number of cancer cases.
  2. Abbreviations: aIR, age adjusted incidence rate; aRR, adjusted relative risk; CI, confidence interval.
  3. a With the combination of frequency and duration with vigorous, sweat-producing leisure-time physical activity (LPA), it was categorized as (1) low; ≤ 4 times/week for < 30 min/session or ≤ 1 time/week for ≥ 30 min/session, (2) moderate; 2–4 times/week for ≥ 30 min/session or ≥ 5 times/week for < 30 min/session, and (3) high; ≥ 5 times/week for ≥ 30 min/session
  4. b The rate is per 100,000 person-years, adjusted to the age distribution of the entire study population.
  5. cThe multivariate relative risk model using standard Poisson regression analysis adjusted for age, dietary preference, amount of alcohol drinking, body mass index, employment and fasting blood sugar as appropriate.