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Table 4 Age-Adjusted Incidence Rate and Relative Risk of Cancer by Smoking Status and Leisure-time Physical activitya

From: Dietary preference, physical activity, and cancer risk in men: national health insurance corporation study

Cancer site Never/Former Smoker Current Smoker
  Low Moderate-High Low Moderate-High
All (n = 2,839) (n = 1,995) (n = 5,494) (n = 3,257)
Age aIRb 478.2 433.6 627.5 570.7
Age aRR (95% CI) 1.00 0.91 (0.86 – 0.96) 1.00 0.91 (0.87 – 0.95)
Multivariate (95% CI)c 1.00 0.91 (0.86 – 0.97) 1.00 0.92 (0.88 – 0.96)
Head and neck (n = 125) (n = 114) (n = 280) (n = 157)
Age aIRb 21.7 25.4 32.3 27.8
Age aRR (95% CI) 1.00 1.17 (0.91 – 1.51) 1.00 0.86 (0.71 – 1.05)
Multivariate (95% CI)c 1.00 1.17 (0.91 – 1.51) 1.00 0.87 (0.71 – 1.05)
Esophagus (n = 37) (n = 26) (n = 152) (n = 78)
Age aIRb 5.2 2.5 15.3 12.1
Age aRR (95% CI) 1.00 0.91 (0.55 – 1.50) 1.00 0.79 (0.60 – 1.04)
Multivariate (95% CI)c 1.00 0.89 (0.54 – 1.47) 1.00 0.82 (0.62 – 1.08)
Stomach (n = 743) (n = 505) (n = 1449) (n = 886)
Age aIRb 123.6 108.5 165.1 154.7
Age aRR (95% CI) 1.00 0.88 (0.78 – 0.98) 1.00 0.94 (0.86 – 1.02)
Multivariate (95% CI)c 1.00 0.88 (0.79 – 0.99) 1.00 0.94 (0.86 – 1.02)
Lung (n = 220) (n = 139) (n = 788) (n = 412)
Age aIRb 36.8 30.1 87.9 71.0
Age aRR (95% CI) 1.00 0.82 (0.66 – 1.01) 1.00 0.81 (0.72 – 0.91)
Multivariate (95% CI)c 1.00 0.82 (0.66 – 1.02) 1.00 0.83 (0.73 – 0.93)
Colorectum (n = 462) (n = 339) (n = 600) (n = 401)
Age aIRb 78.4 74.3 70.3 72.3
Age aRR (95% CI) 1.00 0.95 (0.82 – 1.09) 1.00 1.03 (0.91 – 1.17)
Multivariate (95% CI)c 1.00 0.93 (0.81 – 1.07) 1.00 1.02 (0.90 – 1.16)
Liver (n = 588) (n = 375) (n = 1051) (n = 616)
Age aIRb 94.7 77.6 110.9 99.0
Age aRR (95% CI) 1.00 0.82 (0.72 – 0.93) 1.00 0.89 (0.81 – 0.99)
Multivariate (95% CI)c 1.00 0.86 (0.75 – 0.98) 1.00 0.91 (0.82 – 1.00)
Gallbladder (n = 78) (n = 51) (n = 133) (n = 71)
Age aIRb 13.6 11.5 15.5 12.7
Age aRR (95% CI) 1.00 0.84 (0.59 – 1.20) 1.00 0.82 (0.62 – 1.10)
Multivariate (95% CI)c 1.00 0.85 (0.60 – 1.21) 1.00 0.82 (0.61 – 1.09)
Pancreas (n = 67) (n = 51) (n = 134) (n = 89)
Age aIRb 10.1 10.0 15.6 16.0
Age aRR (95% CI) 1.00 0.99 (0.68 – 1.42) 1.00 1.02 (0.78 – 1.34)
Multivariate (95% CI)c 1.00 0.96 (0.67 – 1.39) 1.00 1.02 (0.78 – 1.34)
Kidney (n = 84) (n = 64) (n = 144) (n = 97)
Age aIRb 14.2 13.9 16.5 17.0
Age aRR (95% CI) 1.00 0.98 (0.71 – 1.36) 1.00 1.03 (0.80 – 1.33)
Multivariate (95% CI)c 1.00 0.94 (0.68 – 1.30) 1.00 1.02 (0.78 – 1.32)
Bladder (n = 68) (n = 60) (n = 177) (n = 103)
Age aIRb 11.2 12.8 20.4 18.3
Age aRR (95% CI) 1.00 1.14 (0.81 – 1.62) 1.00 0.89 (0.70 – 1.14)
Multivariate (95% CI)c 1.00 1.15 (0.81 – 1.63) 1.00 0.89 (0.69 – 1.13)
Prostate (n = 85) (n = 57) (n = 97) (n = 55)
Age aIRb 11.9 10.4 9.8 8.7
Age aRR (95% CI) 1.00 0.88 (0.63 – 1.23) 1.00 0.89 (0.64 – 1.24)
Multivariate (95% CI)c 1.00 0.89 (0.63 – 1.24) 1.00 0.89 (0.64 – 1.24)
  1. The number in the parenthesis means the number of cancer cases.
  2. Abbreviations: aIR, age adjusted incidence rate; aRR, adjusted relative risk; CI, confidence interval.
  3. a With the combination of frequency and duration with vigorous, sweat-producing leisure-time physical activity (LPA), it was categorized as (1) low; ≤ 4 times/week for < 30 min/session or ≤ 1 time/week for ≥ 30 min/session, (2) moderate; 2–4 times/week for ≥ 30 min/session or ≥ 5 times/week for < 30 min/session, and (3) high; ≥ 5 times/week for ≥ 30 min/session
  4. b The rate is per 100,000 person-years, adjusted to the age distribution of the entire study population.
  5. cThe multivariate relative risk model using standard Poisson regression analysis adjusted for age, dietary preference, amount of alcohol drinking, body mass index, employment and fasting blood sugar as appropriate.