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Table 4 Relationship between chromosome 17 copy number and HER2 amplification/HER2 protein expression

From: Analysis of EGFR, HER2, and TOP2A gene status and chromosomal polysomy in gastric adenocarcinoma from Chinese patients

Chromosome 17 Copy number

HER2 FISH

HER2 IHC

 

Negative

Positive

Negative

Positive

Non-polysomy

74

10

79

5

Polysomy

15

1

15

1

Total

89

11

94

6

P value

>0.0026*

>0.0026#

Odds ratio

0.4933

1.0533

  1. *: Association between chromosome 17 polysomy and HER2 amplification.
  2. #: Association between chromosome 17 polysomy and HER2 protein expression.
  3. HER2 FISH Positive: HER2 amplification, HER2 FISH Negative: No HER2 amplification,
  4. HER2 IHC Positive: IHC staining level of 3+, HER2 Negative: IHC staining level of 0,1+,2+
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BMC Cancer

ISSN: 1471-2407

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