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Table 1 Relationship between EGFR copy number and EGFR protein expression

From: Analysis of EGFR, HER2, and TOP2A gene status and chromosomal polysomy in gastric adenocarcinoma from Chinese patients

EGFR IHC

EGFR FISH

Total

 

disomy

Low trisomy

High trisomy

Low polysomy

High polysomy

Amplification

 

Negative

25

11

0

15

7

0

58

Positive

7

13

0

13

6

3

42

Total

32

24

0

28

13

3

100

P value

>0.0026*

Odds ratio

1.987

  1. *: the association between EGFR protein expression and EGFR FISH positive (high polysomy and amplification) and negative (disomy, low trisomy, high trisomy and low polysomy) (P > 0.0026)
  2. EGFR IHC Positive:IHC staining level of 2+and 3+, EGFR IHC Negative:IHC staining level of 0 and 1+.
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BMC Cancer

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