The genetic polymorphisms of HER-2 and the risk of lung cancer in a Korean population

BMC Cancer

Table 6 Comparative analysis between genotype frequencies and the risk of lung cancer in non-smoker groups in adenocarcinoma-controls

Non-smoker	Genotype	Adenocarcinoma (n = 75)	Controls (n = 162)	OR (95% CI)	p-value	asOR (95% CI)^b	p-value
-3444 C>T	CC	26	61	1		1
	CT	33	83	0.93 (0.51 – 1.72)	0.82	0.91 (0.48 – 1.72)	0.77
	TT	16	18	2.09 (0.92 – 4.71)	0.08	2.37 (0.98 – 5.71)	0.06
	CT+TT	49	101	1.14 (0.64 – 2.02)	0.66	1.14 (0.63 – 2.06)	0.68
	CC+CT	59	144	1		1
	TT	16	18	2.17 (1.04 – 4.54)	0.04	2.49 (1.11 – 5.59)	0.03
-1985 G>T	GG	27	61	1		1
	GT	32	82	0.88 (0.48 – 1.62)	0.69	0.88 (0.47 – 1.66)	0.69
	TT	16	19	1.90 (0.85 – 4.25)	0.12	2.10 (0.88 – 5.00)	0.09
	GT+TT	48	101	1.07 (0.61 – 1.90)	0.81	1.09 (0.60 – 1.96)	0.79
	GG+GT	59	143	1		1
	TT	16	19	2.04 (0.98 – 4.24)	0.06	2.26 (1.03 – 5.00)	0.04
P1170A C>G	CC	28	58	1		1
	CG	32	84	0.79 (0.43 – 1.45)	0.44	0.75 (0.40 – 1.41)	0.37
	GG	15	20	1.56 (0.69 – 3.48)	0.28	1.64 (0.69 – 3.91)	0.26
	CG+GG	47	104	0.94 (0.53 – 1.65)	0.82	0.90 (0.50 – 1.64)	0.74
	CC+CG	60	142	1		1
	GG	15	20	1.78 (0.86 – 3.70)	0.13	1.93 (0.87 – 4.27)	0.10

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