The genetic polymorphisms of HER-2 and the risk of lung cancer in a Korean population

BMC Cancer

Table 4 Comparative analysis between genotype frequencies and the risk of lung cancer in the subgroups of non-smokers

Non-smoker	Genotype	Cases (n = 108)	Controls (n = 162)	OR (95% CI)	p-value	asOR (95% CI)^b	p-value
-3444 C>T	CC	36	61	1		1
	CT	48	83	0.98 (0.57 – 1.69)	0.94	0.99 (0.56 – 1.74)	0.96
	TT	24	18	2.26 (1.08 – 4.72)	0.03	2.67 (1.20 – 5.91)	0.02
	CT+TT	72	101	1.21 (0.73 – 2.01)	0.47	1.25 (0.73 – 2.14)	0.41
	CC+CT	84	144	1		1
	TT	24	18	2.29 (1.17 – 4.46)	0.02	2.69 (1.30 – 5.56)	0.01
-1985 G>T	GG	37	61	1		1
	GT	47	82	0.94 (0.55 – 1.63)	0.84	0.97 (0.55 – 1.71)	0.91
	TT	24	19	2.08 (1.01 – 4.31)	0.05	2.41 (1.10 – 5.27)	0.03
	GT+TT	71	101	1.16 (0.70 – 1.93)	0.57	1.21 (0.71 – 2.07)	0.48
	GG+GT	84	143	1		1
	TT	24	19	2.15 (1.11 – 4.16)	0.02	2.46 (1.20 – 5.01)	0.01
P1170A C>G	CC	37	58	1		1
	CG	48	84	0.90 (0.52 – 1.54)	0.69	0.89 (0.50 – 1.57)	0.68
	GG	23	20	1.80 (0.87 – 3.73)	0.11	2.05 (0.94 – 4.47)	0.07
	CG+GG	71	104	1.07 (0.64 – 1.78)	0.79	1.09 (0.64 – 1.86)	0.76
	CC+CG	85	142	1		1
	GG	23	20	1.92 (1.00 – 3.71)	0.05	2.20 (1.08 – 4.47)	0.03

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