Table 2 Clinical findings and family cancer history of the three TP53 R337H carriers
From: Association of the germline TP53R337H mutation with breast cancer in southern Brazil
Patient | Tumor Type | Age Onset | TP53 IHC | Family Cancer History |
|---|---|---|---|---|
1 | Breast; phyllodes, malignant | 19 years | Negative | No cancer |
2 | Breast; invasive ductal carcinoma Brain tumor (malignant) | 29 years 31 years | Negative Positive | Two first-degree relatives (1-U; 1-A) |
3 | Invasive ductal carcinoma | 44 years | Positive | Six first-degree relatives (4-BC; 1-L; 1-ACC) |