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Table 1 Treatment of glioma and melanoma cell lines with 100 μM A-192621 up-regulates DNA damage-inducible genes.

From: Endothelin receptor B antagonists decrease glioma cell viability independently of their cognate receptor

Genes Cell Lines
  LN-229 SW1088 A375 WM35
GADD153 28 12 10 66
GADD45A 23 5 9 8
GADD34 16 3 21 6
Sestrin 2 15 18 19 12
DR5 12 4 10 5
  1. Genes were identified by microarray analysis and real-time RT-PCR was used to quantify the fold-increase in expression over vehicle-treated controls.