TY - JOUR AU - Mendoza-Villanueva, D. AU - Diaz-Chavez, J. AU - Uribe-Figueroa, L. AU - Rangel-Escareão, C. AU - Hidalgo-Miranda, A. AU - March-Mifsut, S. AU - Jimenez-Sanchez, G. AU - Lambert, PF AU - Gariglio, P. PY - 2008 DA - 2008/11/26 TI - Gene expression profile of cervical and skin tissues from human papillomavirus type 16 E6 transgenic mice JO - BMC Cancer SP - 347 VL - 8 IS - 1 AB - Although K14E6 transgenic mice develop spontaneous tumors of the skin epithelium, no spontaneous reproductive tract malignancies arise, unless the transgenic mice were treated chronically with 17β-estradiol. These findings suggest that E6 performs critical functions in normal adult cervix and skin, highlighting the need to define E6-controlled transcriptional programs in these tissues. SN - 1471-2407 UR - https://doi.org/10.1186/1471-2407-8-347 DO - 10.1186/1471-2407-8-347 ID - Mendoza-Villanueva2008 ER -