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Table 3 Association of metastatic stage of colorectal cancer diagnosis with comorbidity, age, and race in two patient cohorts

From: Comorbidity, age, race and stage at diagnosis in colorectal cancer: a retrospective, parallel analysis of two health systems

Characteristic VA FFS
  OR (95% CI) p-value OR (95% CI) p-value
Comorbidity     
   Unadjusted 0.78 (0.61, 1.00) 0.04 1.08 (0.82, 1.42) 0.59
   Adjusted 0.76 (0.58, 1.00) 0.045 1.09 (0.82, 1.44) 0.57
Age (≥ 70 years)     
   Unadjusted 0.98 (0.79, 1.23) 0.88 0.97 (0.80, 1.18) 0.76
   Adjusted 1.08 (0.85, 1.36) 0.54 0.96 (0.78, 1.17) 0.67
Race (white)     
   Unadjusted 0.80 (0.49, 1.31) 0.39 1.12 (0.61, 2.08) 0.72
   Adjusted 0.83 (0.51, 1.37) 0.47 1.12 (0.60, 2.09) 0.72
  1. Adjusted odds ratios were calculated from a multivariable logistic regression model that included Charlson comorbidity score (modelled as an integer-valued quantitative variable), age at diagnosis (expressed in years), and race (white vs non-white). The unadjusted and adjusted odds ratios, shown here with associated 95% confidence intervals and p-values, are for a single unit increase in comorbidity, a decade increase in age, and the comparison of white vs. non-white for race. Final n for VA adjusted model = 336 (91 metastatic, 245 non-metastatic), final n for FFS adjusted model = 270 (198 metastatic, 72 non-metastatic).