Figure 3

The effects of YSL plus mid-dose doxorubicin on the hematological indices of nude mice bearing human hepatocellular carcinoma BEL-7402 tumors. BEL-7402 cell (1 × 10⁷/every mouse) was subcutaneously inoculated into the right back of every nude mouse. When the tumors had reached an average volume of 100 mm³, the tumor-bearing nude mice were randomly divided into different groups (n = 12). Drugs delivered by i.p. injection for 30 days successively. At the next day of the last administration, blood was obtained from angular vein of nude mice, then blood was anticoagulated by heparin, we detected hematoglobin level and counted PLT and WBC. All data were analyzed by one-way analysis of variance using SPSS. The difference between two groups was analyzed by the Student-Newman-Keuls test. Standard deviation was represented by error line. *P < 0.05 as compared to the saline group. ADM, doxorubicin or adriamycin; YSL, tripeptide tyroserleutide. WBC, white blood cells; PLT, platelets; Hb, hemoglobin.