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Table 3 Multivariate Cox Regression Survival Analysis with Dichotomised Scored Monocyte IL-6 Secretion (serum-free medium) Adjusted for Gender and Age (upper panel), or adjusted for Gender, Age and TN stage (lower panel) of HNSCC Patients

From: Stimulated monocyte IL-6 secretion predicts survival of patients with head and neck squamous cell carcinoma

 

Total survival

Disease-specific survival

 

HR

95% CI (HR)

P value

HR

95% CI (HR)

P value

Gender

0.52

0.18–1.52

0.236

0.35

0.10–1.31

0.119

Age

1.07

1.02–1.11

0.002

1.08

1.03–1.28

0.002

IL-6

2.27

1.05–4.88

0.036

2.68

1.11–6.45

0.028

Gender

0.54

0.20–1.50

0.237

0.40

0.11–1.41

0.153

Age

1.06

1.02–1.11

0.008

1.06

1.01–1.11

0.025

T stage

1.64

1.18–2.29

0.003

1.89

1.29–2.79

0.001

N stage

1.55

1.06–2.28

0.025

1.61

1.03–2.51

0.035

IL-6

2.08

0.97–4.48

0.061

2.44

1.01–5.92

0.049

  1. HR = Hazard ratio 95% CI(HR) = 95% confidence interval for HR