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Table 4 Univariate and multivariate analyses of 14-gene signature and Ki-67 LI for distant-metastasis-free survival (DMFS) and overall survival (OS)

From: Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature

   Univariate analysis Multivariate analysis
Endpoint Variable Hazard ratio (95% CI) p-value Hazard ratio (95% CI) p-value
DMFS 14-gene signature 4.34 (1.86–10.1) 0.001 3.64 (1.49–8.90) 0.005
  Ki-67 LI 2.40 (1.12–5.11) 0.024 1.55 (0.69–3.45) 0.286
OS 14-gene signature 2.48 (1.42–4.32) 0.001 2.21 (1.23–3.97) 0.008
  Ki-67 LI 1.71 (1.00–2.93) 0.049 1.32 (0.75–2.33) 0.332
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