TY - JOUR AU - Tutt, Andrew AU - Wang, Alice AU - Rowland, Charles AU - Gillett, Cheryl AU - Lau, Kit AU - Chew, Karen AU - Dai, Hongyue AU - Kwok, Shirley AU - Ryder, Kenneth AU - Shu, Henry AU - Springall, Robert AU - Cane, Paul AU - McCallie, Blair AU - Kam-Morgan, Lauren AU - Anderson, Steve AU - Buerger, Horst AU - Gray, Joe AU - Bennington, James AU - Esserman, Laura AU - Hastie, Trevor AU - Broder, Samuel AU - Sninsky, John AU - Brandt, Burkhard AU - Waldman, Fred PY - 2008 DA - 2008/11/21 TI - Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature JO - BMC Cancer SP - 339 VL - 8 IS - 1 AB - Given the large number of genes purported to be prognostic for breast cancer, it would be optimal if the genes identified are not confounded by the continuously changing systemic therapies. The aim of this study was to discover and validate a breast cancer prognostic expression signature for distant metastasis in untreated, early stage, lymph node-negative (N-) estrogen receptor-positive (ER+) patients with extensive follow-up times. SN - 1471-2407 UR - https://doi.org/10.1186/1471-2407-8-339 DO - 10.1186/1471-2407-8-339 ID - Tutt2008 ER -