From: Elevation of circulating big endothelin-1: an independent prognostic factor for tumor recurrence and survival in patients with esophageal squamous cell carcinoma
Variable
Hazard Ratio
95% Confidence Interval
P value
Tumor class
2.878
1.805–4.576
0.010
Lymph node status
2.921
1.951–3.988
0.015
Stage
3.083
1.259–5.731
0.002
Plasma big ET-1 levels
2.629
1.375–4.054
0.003