Table 3 Breast cancer patients' pre-diagnosis and follow-ups symptoms scores as measured by the EORTC QLQ-C30* (n = 99)

Fatigue

17.0 (19.4)

31.0 (25.4)

36.0 (21.8)

<0.001

Nausea and vomiting

1.7 (7.3)

29.3 (30.5)

2.5 (10.7)

<0.001

Pain

4.5 (9.7)

4.5 (10.6)

15.3 (21.0)

<0.001

Dyspnea

5.7 (14.3)

8.7 (16.2)

14.8 (21.9)

<0.001

Sleep difficulties

27.5 (30.2)

25.2 (30.3)

26.9 (27.3)

<0.001

Appetite loss

20.9 (29.2)

35.7 (32.4)

6.7 (18.4)

<0.001

Constipation

2.3 (9.8)

9.1 (19.5)

10.1 (19.9)

<0.001

Diarrhea

0.33 (3.3)

2.0 (9.3)

1.0 (5.7)

0.003

Financial difficulties

17.7 (25.8)

22.1 (27.0)

23.1 (28.5)

<0.001