Figure 2

Heatmap of total gene expression changes and cluster analysis after incubation with doxorubicin for 24 h. Horizontal rows represent individual genes; vertical columns represent individual samples. Color range: Brightest red (Change call increased (change p-value < 0.002) and Signal Log Ratio > 1): SLR = >2 (4× or higher), Black: SLR = 0 (no change); not visible as a consequence of the filtering process, Brightest green (Change call decreased (change p-value > 0.998) and Signal Log Ratio < -1): SLR < -2 (0.25× or smaller). Grey: no value (requirements for a reliably measured target not met). Calculated in Affymetrix comparison analysis (MAS5.0 algorithm) and at least one present call in the two síngle array analyses compared in the comparison analysis. The dendogram at the left side indicates the degree of similarity among the selected genes according to their expression patterns (the higher the dendogramm, the lower the similarity). MR: Myxoid/Roundcell Liposarcoma, PL: Pleomorphic Liposarcoma, AL: Atypical Lipoma, ML: Myxoid Liposarcoma, DL: Dedifferentiated Liposarcoma, low: low responder group, medium: medium responder group, high: high responder group.