Figure 5From: STAT3 can be activated through paracrine signaling in breast epithelial cells Addition of IL-6 is sufficient to increase levels of p-STAT3 in MDA-MB-453 and MCF-10A cell lines. A. MDA-MB-453 cells were treated with 50 ng/ml IL-6 for 30 minutes. B. MCF-10A cells were treated with 25 ng/ml IL-6 for 30 minutes.Back to article page