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Table 2 Summary of results.

From: Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1genes

  All CMMLs
(N = 30)
All non AT-CMMLs
(N = 24)
MP-CMMLs
(N = 13)
MD-CMMLs
(N = 11)
AT-CMMLs
(N = 6)
RUNX1
alteration
Normal-like 17 16 6 10 1 7
Trisomy 8 3 2 2 0 1 3
Del20q 4 2 1 1 2 3
RAS pathway mutation 7 6 6 0 1 4
RUNX1 alteration 11 8 5 3 3 11
RUNX1 mutation 9 8 5 3 1 9
USP16-RUNX1 2 0 0 0 2 2
  1. RAS pathway mutations include point mutations in KRAS, NRAS and PTPN11. RUNX1 alterations include RUNX1 mutations and breaks. Two cases (1 AT and 1 non-AT) are from the same patient.