From: Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1genes
All CMMLs (N = 30) | All non AT-CMMLs (N = 24) | MP-CMMLs (N = 13) | MD-CMMLs (N = 11) | AT-CMMLs (N = 6) | RUNX1 alteration | |
---|---|---|---|---|---|---|
Normal-like | 17 | 16 | 6 | 10 | 1 | 7 |
Trisomy 8 | 3 | 2 | 2 | 0 | 1 | 3 |
Del20q | 4 | 2 | 1 | 1 | 2 | 3 |
RAS pathway mutation | 7 | 6 | 6 | 0 | 1 | 4 |
RUNX1 alteration | 11 | 8 | 5 | 3 | 3 | 11 |
RUNX1 mutation | 9 | 8 | 5 | 3 | 1 | 9 |
USP16-RUNX1 | 2 | 0 | 0 | 0 | 2 | 2 |