Table 3 Frequency of AI by HER2 status at 26 chromosomal regions
From: Amplification of HER2 is a marker for global genomic instability
Chromosomal Region | HER2+ | HER2- | P HER2+ v HER2- |
|---|---|---|---|
1p36.1-p36.2 | 0.25 (36) | 0.12 (140) | 0.0658 |
2q21.3-23.3 | 0.14 (36) | 0.15 (130) | 1.0000 |
3p14.1 | 0.19 (36) | 0.18 (129) | 0.8100 |
5q21.1-q21.3 | 0.23 (35) | 0.16 (133) | 0.3233 |
6q15 | 0.18 (38) | 0.20 (133) | 1.0000 |
6q22.1-q23.1 | 0.25 (37) | 0.16 (134) | 0.2286 |
6q25.2-q27 | 0.32 (37) | 0.20 (136) | 0.1219 |
7q31.1-q31.31 | 0.20 (35) | 0.08 (133) | 0.0523 |
8p22-p21.3 | 0.26 (35) | 0.18 (130) | 0.3476 |
8q24 | 0.26 (39) | 0.16 (129) | 0.1577 |
9p21 | 0.20 (35) | 0.12 (129) | 0.2607 |
10q23.31-q23.33 | 0.14 (37) | 0.15 (132) | 1.0000 |
11p15 | 0.26 (35) | 0.18 (133) | 0.3411 |
11q13.1 | 0.33 (39) | 0.19 (137) | 0.0790 |
11q23 | 0.50 (36) | 0.23 (128) | 0.0033 |
13q12.3 | 0.27 (37) | 0.30 (130) | 0.6641 |
13q14.2-q14.3 | 0.29 (39) | 0.18 (133) | 0.1790 |
14q32.11-q31 | 0.18 (38) | 0.20 (131) | 1.0000 |
16q11.2-q22.1 | 0.30 (37) | 0.30 (134) | 1.0000 |
16q22.3-q24.3 | 0.50 (36) | 0.26 (129) | 0.0076 |
17p13.3 | 0.43 (30) | 0.26 (117) | 0.0789 |
17p13.1 | 0.33 (39) | 0.28 (137) | 0.5564 |
17q12-q21 | 0.26 (38) | 0.17 (133) | 0.2367 |
18q21.1-q21.3 | 0.27 (37) | 0.13 (128) | 0.0416 |
22q12.3 | 0.27 (38) | 0.15 (132) | 0.4565 |
22q13.1 | 0.33 (39) | 0.26 (134) | 0.6639 |