Table 2 Results of statistical analyses of associations between D-loop mtDNA mutation and clinicopathologic parameters in 44 ovarian cancer patients

Overall

44

25

19

Age (median = 53)

> 53

19

13

7

≤ 53

24

12

12

0.3175

Grading

G2 + G3

31

20

11

G4

12

5

7

0.3014

FIGO stage

II-IIIB

10

5

5

IIIC, IV

34

20

14

0.7233

Residual tumour

> 2 cm

14

9

5

0–2 cm

29

16

14

0.534

TP53 mutation

Yes

23

14

9

No

20

11

10

0.7613

Response to chemotherapy

Platinum-based

Yes

10

5

5

No

9

5

4

1

Taxane/platinum-based

Yes

12

9

3

No

12

6

7

0.2262

Both types of therapy

Yes

22

14

8

No

21

11

11

0.5434

Haplogroups

H

22

14

9

Others

21

11

10

0.7613