Nuclear hBD-1 accumulation in malignant salivary gland tumours

Wenghoefer, M; Pantelis, A; Dommisch, H; Götz, W; Reich, R; Bergé, S; Martini, M; Allam, JP; Jepsen, S; Merkelbach-Bruse, S; Fischer, HP; Novak, N; Winter, J

doi:10.1186/1471-2407-8-290

BMC Cancer

Table 1 Location of hBD-1, -2, -3, p53 and bcl-2 in malignant, benign and healthy salivary gland tissues (positive ++, weak positive +, negative -)

From: Nuclear hBD-1 accumulation in malignant salivary gland tumours

tumour	behaviour	hBD-1	hBD-2	hBD-3	bcl-2	p53
salivary duct carcinoma	malignant	nucleus (and cytoplasm+)	cytoplasm++	cytoplasm ++	negative-	positive+
mucoepidermoid carcinoma	malignant	nucleus++ (and cytoplasm+)	cytoplasm++	cytoplasm++	positive++	positive+
adenoid cystic carcinoma	malignant	nucleus++	cytoplasm++	cytoplasm++ and nucleus+	negative-	positive+
adenoid cystic carcinoma	malignant	nucleus++	cytoplasm++	cytoplasm++	negative-	negative
adenoid cystic carcinoma	malignant	nucleus++	cytoplasm++	cytoplasm++	negative-	negative
carcinosarcoma	malignant	nucleus++	cytoplasm++	cytoplasm++	positive++	positive+
adenocarcinoma	malignant	nucleus++	cytoplasm++	cytoplasm++	positive++	positive+
pleomorphic adenoma	benign	cytoplasm++ (and nucleus+)	cytoplasm++	cytoplasm++	positive++	negative
pleomorphic adenoma	benign	cytoplasm++ (and nucleus+)	cytoplasm++	cytoplasm++	positive++	negative
pleomorphic adenoma	benign	cytoplasm++ (and nucleus+)	cytoplasm++	cytoplasm++	positive++	negative
cystadenolymphoma	benign	cytoplasm++	cytoplasm	cytoplasm++	negative-	negative
cystadenolymphoma	benign	cytoplasm++	cytoplasm	cytoplasm++	positive++	negative
oncocytoma	benign	cytoplasm++	cytoplasm	cytoplasm++	positive++	weak positive+
oncocytoma	benign	cytoplasm++	cytoplasm++	cytoplasm++	positive++	weak positive+
healthy salvary gland tissue 1	healthy	cytoplasm++	cytoplasm+	cytoplasm++	negative-	negative
healthy salvary gland tissue 2	healthy	cytoplasm++	cytoplasm++	cytoplasm++	negative-	negative
healthy salvary gland tissue 3	healthy	cytoplasm+	cytoplasm++	cytoplasm++	negative-	negative
healthy salvary gland tissue 4	healthy	cytoplasm++	cytoplasm+	cytoplasm++	negative-	negative
healthy salvary gland tissue 5	healthy	cytoplasm++	cytoplasm+	cytoplasm++	negative-	negative
healthy salvary gland tissue 6	healthy	cytoplasm++	cytoplasm++	cytoplasm+	negative-	negative
healthy salvary gland tissue 7	healthy	cytoplasm++	cytoplasm++	cytoplasm++	negative-	negative

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