Table 2 Protein expression in the epithelium (cells/mm2) of different studied markers in the uterine cervix from HPV+/HIV-negative infection
Marker | VEGF | P27 | Rb | Elf-1 |
|---|---|---|---|---|
Chronic cervicitis | ||||
Mean (SD) | 36.73 (52.37) | 0.19 (0.73) | 12.5 (17.6) | 76.26 (59.27) |
Median (IQR) | 0 (0 – 51.5) | 0 (0–0) | 0 (0 – 20) | 65 (39 – 95) |
(n) | n = 33 | n = 32 | n = 27 | n = 27 |
CIN I | ||||
Mean (SD) | 102.5 (73.8) | 8.25 (20.5) | 17.9 (31.6) | 63.8 (70.4) |
Median (IQR) | 74 (17.5 – 105.75) | 0 (0 – 0) | 0 (0 – 25.50) | 20 (4 – 78) |
** | ||||
(n) | n = 32 | n = 31 | n = 29 | n = 27 |
CIN II/III | ||||
Mean (SD) | 127.7 (85.9) | 9.26 (23.1) | 4.8 (16.4) | 115.7 (88.3) |
Median (IQR) | 77 (47 – 136) | 0 (0 – 2.75) | 0 (0 – 0) | 99 (40 – 203) |
** | ** | |||
(n) | n = 41 | n = 32 | = 41 | n = 35 |
Tumor | ||||
Mean (SD) | 163.1 (187.36) | 3.0 (3.0) | 3.9 (12.3) | 112 (87.6) |
Median (IQR) | 96 (43 – 248.5) | 3 (0 – 6) | 0 (0–.0) | 101 (35. 5–166) |
** | ||||
(n) | n = 9 | n = 9 | n = 10 | n = 9 |
p-value* | < 0.001 | 0.047 | 0.003 | 0.005 |