Skip to main content

Table 4 Apoptosis-related factors in DCIS and DCIS-Mi

From: Identification of biomarkers in ductal carcinoma in situ of the breast with microinvasion

 

DCIS

DCIS-Mi

P-value

Apoptotic Index (N/1000)

1.7 ± 0.4

2.9 ± 0.6

0.082

Bcl-2

   

   negative

21 (41.2%)

6 (21.4%)

0.071

   Positive

30 (58.8%)

22 (78.6%)

 

Bax

   

   negative

15 (28.8%)

1 (3.6%)

0.0028

   Positive

37 (71.2%)

27 (96.4%)

 

Survivin

   

   negative

23 (44.2%)

4 (14.3%)

0.0048

   positive

29 (55.8%)

24 (85.7%)

 

p53

   

   positive

39 (76.5%)

23 (82.1%)

0.55

   Negative

12 (23.5%)

5 (17.9%)

 

p21

   

   positive

36 (69.2%)

15 (53.6%)

0.17

   negative

16 (30.8%)

13 (46.4%)

 

cyclinD1

   

   positive

36 (70.6%)

18 (64.3%)

0.57

   Negative

15 (29.4%)

10 (35.7%)

 

Rb

   

   positive

35 (68.6%)

23 (82.1%)

0.18

   negative

16 (31.4%)

5 (17.9%)

 
  1. DCIS = ductal carcinoma in situ; DCIS-Mi = ductal carcinoma in situ with microinvasion.