From: Identification of biomarkers in ductal carcinoma in situ of the breast with microinvasion
 | DCIS | DCIS-Mi | P-value |
---|---|---|---|
Apoptotic Index (N/1000) | 1.7 ± 0.4 | 2.9 ± 0.6 | 0.082 |
Bcl-2 | Â | Â | Â |
   negative | 21 (41.2%) | 6 (21.4%) | 0.071 |
   Positive | 30 (58.8%) | 22 (78.6%) |  |
Bax | Â | Â | Â |
   negative | 15 (28.8%) | 1 (3.6%) | 0.0028 |
   Positive | 37 (71.2%) | 27 (96.4%) |  |
Survivin | Â | Â | Â |
   negative | 23 (44.2%) | 4 (14.3%) | 0.0048 |
   positive | 29 (55.8%) | 24 (85.7%) |  |
p53 | Â | Â | Â |
   positive | 39 (76.5%) | 23 (82.1%) | 0.55 |
   Negative | 12 (23.5%) | 5 (17.9%) |  |
p21 | Â | Â | Â |
   positive | 36 (69.2%) | 15 (53.6%) | 0.17 |
   negative | 16 (30.8%) | 13 (46.4%) |  |
cyclinD1 | Â | Â | Â |
   positive | 36 (70.6%) | 18 (64.3%) | 0.57 |
   Negative | 15 (29.4%) | 10 (35.7%) |  |
Rb | Â | Â | Â |
   positive | 35 (68.6%) | 23 (82.1%) | 0.18 |
   negative | 16 (31.4%) | 5 (17.9%) |  |