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Table 1 Genotype frequencies of MDM2 SNP309 in Scottish Caucasian control and breast cancer populations

From: MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism

309 SNP Total 309T/T 309T/G 309G/G
  n n (%) n (%) n (%)
Control samples 275 123 (44.7) 116 (42.2) 36 (13.1)
Males 93 48 (51.6) 34 (36.6) 11 (11.8)
Females 182 78 (42.8) 79 (43.4) 25 (13.7)
Breast cancer samples 299 118 (39.5) 141 (47.2) 40 (13.4)
Breast cancer vs. Female controls OR (95% CI)   1.0 (referent) 1.18 (0.80 – 1.87) 1.06 (0.60 – 1.87)
p value   - 0.41 0.85
  1. MDM2 SP309 genotype frequencies in Scottish Caucasian control and breast cancer populations. OR = Odds ratio, CI = Confidence interval.