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Table 1 Genotype frequencies of MDM2 SNP309 in Scottish Caucasian control and breast cancer populations

From: MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism

309 SNP

Total

309T/T

309T/G

309G/G

 

n

n (%)

n (%)

n (%)

Control samples

275

123 (44.7)

116 (42.2)

36 (13.1)

Males

93

48 (51.6)

34 (36.6)

11 (11.8)

Females

182

78 (42.8)

79 (43.4)

25 (13.7)

Breast cancer samples

299

118 (39.5)

141 (47.2)

40 (13.4)

Breast cancer vs. Female controls

OR (95% CI)

 

1.0

(referent)

1.18

(0.80 – 1.87)

1.06

(0.60 – 1.87)

p value

 

-

0.41

0.85

  1. MDM2 SP309 genotype frequencies in Scottish Caucasian control and breast cancer populations. OR = Odds ratio, CI = Confidence interval.