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Figure 1 | BMC Cancer

Figure 1

From: The effects of timing of fine needle aspiration biopsies on gene expression profiles in breast cancers

Figure 1

Differential gene expression pattern of breast cancers between FNABs taken pre-operatively (PRE) and post-operatively (POST). (A) Hierarchical clustering pattern of expression of 14 cDNA probes between PRE and POST FNABs (p < 0.05, t-test). Rows represent cDNA probes and columns represent FNAB samples. "PRE" and "POST" correspond to pre and post-operative biopsies for the respective samples. The expression level is depicted according to the color scale (bottom) which represents the Log2 ratio changes of the samples relative to the human universal reference RNA (Stratagene). Grey squares indicate missing or filter-excluded data. (B) Validation of FOS gene expression in cDNA microarray using qRT-PCR. qRT-PCR data shown are averages of duplicate measurements. The columns correspond to FOS expression data in the microarray and qRT-PCR from PRE and POST specimens. The rows represent the corresponding specimens. Each cell in the matrix represents the expression level of Log2 ratio for microarray or Log ratio for qRT-PCR relative to the human universal reference RNA (Stratagene).

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