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Table 3 Association of Cyclin D1 870 G>A (rs603965) Polymorphism and Family History of Colorectal Cancer in Endometrial Cancer Cases

From: The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor

Genotype

FH of Colorectal Cancer in Endometrial Cancer Cases (n = 191)

χ2

OR (95% CI) and p value

 

Yes n (%)

No n (%)

   

GG

6 (3.1)

43 (22.5)

p = 0.084

1.00 (reference)

 

GA

16 (8.4)

78 (40.8)

 

1.470 (0.536–4.034)

p = 0.454

AA

14 (7.3)

34 (17.8)

 

2.951 (1.026–8.491)

p = 0.045

GA+AA

30 (15.7)

112 (58.6)

p = 0.170#

1.920 (0.747–4.936)

p = 0.176

GG+GA

22 (11.5)

121 (63.4)

p = 0.035

2.265 (1.048–4.894)

p = 0.038

  1. Note: FH, family history.
  2. # p value: Wild type genotype (GG) compared to combination of heterozygous and homozygous variant genotypes (GA+AA).
  3. † p value: Homozygous variant genotype (AA) compared to combination of wild type and heterozygous genotypes (GG+GA).