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Table 3 Association of Cyclin D1 870 G>A (rs603965) Polymorphism and Family History of Colorectal Cancer in Endometrial Cancer Cases

From: The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor

Genotype FH of Colorectal Cancer in Endometrial Cancer Cases (n = 191) χ2 OR (95% CI) and p value
  Yes n (%) No n (%)    
GG 6 (3.1) 43 (22.5) p = 0.084 1.00 (reference)  
GA 16 (8.4) 78 (40.8)   1.470 (0.536–4.034) p = 0.454
AA 14 (7.3) 34 (17.8)   2.951 (1.026–8.491) p = 0.045
GA+AA 30 (15.7) 112 (58.6) p = 0.170# 1.920 (0.747–4.936) p = 0.176
GG+GA 22 (11.5) 121 (63.4) p = 0.035 2.265 (1.048–4.894) p = 0.038
  1. Note: FH, family history.
  2. # p value: Wild type genotype (GG) compared to combination of heterozygous and homozygous variant genotypes (GA+AA).
  3. † p value: Homozygous variant genotype (AA) compared to combination of wild type and heterozygous genotypes (GG+GA).