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Table 2 Association of Cyclin D1 870 G>A (rs603965) Polymorphism with Endometrial Cancer Risk

From: The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor

Genotype Cases n (%) Controls n (%) χ2 OR (95% CI) and p value
GG 49 (25.7) 93 (32.1) p = 0.161 1.00 (reference)  
     1.262 (0.771–2.066)adj# p = 0.355
     1.256 (0.815–1.938) p = 0.302
AA 48 (25.1) 55 (19.0)   1.692 (0.939–3.049)adj# p = 0.080
     1.656 (0.989–2.784) p = 0.057
GA+AA 142 (74.3) 197 (67.9) p = 0.131 1.383 (0.869–2.201)adj# p = 0.172
     1.368 (0.910–2.057) p = 0.132
GG+GA 143 (74.9) 235 (81.0) p = 0.107 1.458 (0.889–2.393)adj# p = 0.135
     1.434 (0.924–2.226) p = 0.108
  1. Note: Minor Allele Frequency (MAF) 0.317.
  2. # ORadj: Adjusted for BMI, HBP, diabetes, HT, personal history of cancer, smoking and alcohol use.
  3. † p value: Wild type genotype (GG) compared to combination of heterozygous and homozygous variant genotypes (GA+AA).
  4. ‡ p value: Homozygous variant genotype (AA) compared to combination of wild type and heterozygous genotypes (GG+GA).