Figure 1

Principal components analysis (PCA) and unsupervised hierarchical clustering into distinct mammary-tumor phenotypes. Mammary carcinoma and adenocarcinoma tumors were developed in transgenic mice expressing the forced activated Stat5 (STAT5ca) or truncated Stat5 (STAT5Δ750). PCA (A) and unsupervised hierarchical clustering (standard correlation, B) were performed on genes that were expressed at significantly (P < 0.05) different levels between phenotypes and confirmed the distinction of the two phenotypes.