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Table 5 TP53-positive group. Cumulated hazards of death in patients with various combinations of age and tumor grade (the hazards are based on multivariate models).

From: TP53 status and taxane-platinum versus platinum-based therapy in ovarian cancer patients: A non-randomized retrospective study

Age Tumor grade Cumulated hazards PC/PAC Cumulated hazards TP
≤53 2 1 0.15
≤53 3 1 0.86
≤53 4 1 0.90
>53 2 1 0.08
>53 3 1 0.50
>53 4 1 0.52
  1. The hazards of death are strikingly lower for taxane-platinum therapy in patients older than 53 years or with grade 2 tumors. For other patients the hazards for the two chemotheraputic regimens are close.