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Table 4 Gene Ontology terms that are enriched among the top CREB targets.

From: Expression profile of CREB knockdown in myeloid leukemia cells

Category

Term

Count

%

PValue

GOTERM_CC_ALL

nucleosome

11

6.88%

6.22E-10

GOTERM_CC_ALL

chromosome

17

10.62%

2.39E-09

GOTERM_BP_ALL

nucleosome assembly

11

6.88%

6.60E-09

GOTERM_CC_ALL

chromatin

13

8.12%

7.56E-09

GOTERM_BP_ALL

chromatin assembly

11

6.88%

1.66E-08

GOTERM_BP_ALL

protein complex assembly

15

9.38%

2.19E-07

GOTERM_BP_ALL

chromatin assembly or disassembly

11

6.88%

3.84E-07

GOTERM_BP_ALL

chromosome organization and biogenesis

15

9.38%

5.56E-07

GOTERM_BP_ALL

chromosome organization and biogenesis (sensu Eukaryota)

14

8.75%

1.63E-06

GOTERM_CC_ALL

membrane-bound organelle

75

46.88%

1.93E-06

GOTERM_CC_ALL

intracellular membrane-bound organelle

74

46.25%

4.63E-06

GOTERM_CC_ALL

organelle

83

51.88%

5.39E-06

GOTERM_MF_ALL

DNA binding

38

23.75%

6.17E-06

GOTERM_BP_ALL

cellular physiological process

118

73.75%

8.86E-06

GOTERM_BP_ALL

establishment and/or maintenance of chromatin architecture

12

7.50%

1.02E-05

GOTERM_CC_ALL

intracellular organelle

82

51.25%

1.28E-05

GOTERM_BP_ALL

DNA packaging

12

7.50%

1.38E-05

GOTERM_BP_ALL

organelle organization and biogenesis

22

13.75%

1.59E-05

GOTERM_CC_ALL

nucleus

56

35.00%

2.46E-05

GOTERM_BP_ALL

DNA metabolism

19

11.88%

2.63E-05

  1. Column 1 is the ontology used (BP is biological process, CC is cellular localization and MF is molecular function), column 2 is the term, column 3 is the number of genes in the target list associated wit the term, column 4 is the percentage of genes in the target list associated with the term and column 5 is the P value for observing this number genes associated with the term.