Overlapping of CpG island with BRD7 promoter. (A) A CpG island spanning from -481 to -56 bp upstream of BRD7 gene identified by EMBOSS CpGplot program. (B) Schematic representation of BRD7 promoter -404/+46 (marked with the square) and the CpG island in the upstream sequence of BRD7 gene. The CpG island (hatched box) of BRD7 gene was predicted by EMBOSS CpGplot program whereas the CpG island (diamond-shaped box) of BRD7 gene was predicted by the Softberry CpGFinder program. The translation start site is position +1 and the rest of the sequence is numbered relative to it.