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Table 1 Distribution of HPV-16 variants in cervical biopsies from HPV-16 positive ICC cases

From: Interaction between polymorphisms of the Human Leukocyte Antigen and HPV-16 Variants on the risk of invasive cervical cancer

Branch

Variants

E6 substitutionsa

All HPV-16 cases

HPV-16 exclusivelyd

  

10

14

78

83

Carriers (%)b n = 107c

Carriers (%) n = 69

E

     

54 (50.5)

28 (40.6)

 

E-P

A

Q

H

L

49 (45.8)

23 (33.3)

 

E-350G

-

-

-

V

4

3

 

E-6994 A

-

-

-

-

1

1

 

E-G131T

G

-

-

-

1

1

AA

     

59 (55.1)

 
 

AAa

-

H

Y

V

58 (54.2)

37 (53.6)

 

NA-1

-

H

Y

V

1

0

Af-1

Af-1

T

D

Y

-

1

0

Af-2

Af-2

I

D

Y

-

8 (7.5)

4 (5.7)

  1. a) -: Residue identical to the E-P;
  2. b) Percentages are shown only for variant branches and for the most common variant groups;
  3. c) The total number of HPV-16 variants exceeds 107 because we included cases with infection by more than one variant;
  4. d) Co-infections with other types excluded.
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BMC Cancer

ISSN: 1471-2407

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