Table 1 Characteristics of lung cancer patients recruited to GELCAPS
| Â | Cases | Controls |
|---|---|---|
Total | 5,269 | 2,094 |
Gender (Male: Female) | 3,382 (64.2%) | 645 (30.8%) |
Age at diagnosis (years) | 887 (35.8%) | 446 (69.1%) |
   <40 | 53 (1.0%) | 64 (3.1%) |
   40–49 | 302 (5.7%) | 166 (7.9%) |
   50–59 | 1,146 (21.7%) | 514 (24.5%) |
   60–69 | 1,868 (35.4%) | 756 (36.1%) |
   70–79 | 1,590 (30.1%) | 510 (24.4%) |
   80+ | 310 (5.9%) | 84 (4.0%) |
   Mean (SD) | 65.1 (10.0) | 62.9 (10.6) |
Ethnicity | Â | Â |
   Arabic | 3 (0.05%) | 1 (0.05%) |
   Asian | 7 (0.13%) | 6 (0.29%) |
   Bangladeshi | 1 (0.01%) | 0 |
   Black-African | 4 (0.08%) | 1 (0.05%) |
   Black-Caribbean | 31 (0.59%) | 8 (0.38%) |
   Black-Other | 1 (0.01%) | 0 |
   Indian | 16 (0.30%) | 4 (0.19%) |
   Jewish-Ashkenazi | 12 (0.22%) | 6 (0.29%) |
   Pakistani | 8 (0.15%) | 0 |
   White | 5,065 (96.1%) | 1,947 (93.0%) |
   Other/not specified | 82 (1.6%) | 121 (5.8%) |
Reported asbestos exposure | 807 (15.2%) | 125 (6.0%) |
Family history of lung cancer | 750 (14.2%) | 212 (10.1%) |
Smoking habits | Â | Â |
   Never-smokers | 307 (5.8%) | 718 (34%) |
   All smokers |  |  |
   Age first started smoking (SD) | 16.5 (4.0) | 17.9 (4.8%) |
   Pack years in Smokers (SD) | 47.2 (30.6) | 30.4 (22.1%) |
Histology of cancer | Â | Â |
Small cell (SCLC) | 1,193 (22.6%) | Â |
Non-small cell (NSCLC) | 3,815 (72.4%) | Â |
   Squamous | 1,905 (49.9%) |  |
   Adenocarcinoma (including variants) | 1,110 (29.1%) |  |
   Large cell | 10 (0.3%) |  |
   Brochoalveolar | 44 (1.2%) |  |
   Adenosquamous | 11 (0.3%) |  |
   Neuroendocrine | 20 (0.5%) |  |
   NSCLC unspecified | 715 (18.7%) |  |
Sarcoma | 5 (0.1%) | Â |
Unclassified primary | 256 (4.9%) | Â |
Tumour stage at presentation, by histology | Â | Â |
   SCLC |  |  |
Limited | 168 (50.4%) | Â |
Extensive | 165 (59.6%) | Â |
   NSCLC |  |  |
I | 151 (14.1%) | Â |
II | 140 (13.1%) | Â |
III | 457 (42.7%) | Â |
IV | 323 (30.2%) | Â |