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Table 1 Characteristics of lung cancer patients recruited to GELCAPS

From: Identification of low penetrance alleles for lung cancer: The GEnetic Lung CAncer Predisposition Study (GELCAPS)

  Cases Controls
Total 5,269 2,094
Gender (Male: Female) 3,382 (64.2%) 645 (30.8%)
Age at diagnosis (years) 887 (35.8%) 446 (69.1%)
   <40 53 (1.0%) 64 (3.1%)
   40–49 302 (5.7%) 166 (7.9%)
   50–59 1,146 (21.7%) 514 (24.5%)
   60–69 1,868 (35.4%) 756 (36.1%)
   70–79 1,590 (30.1%) 510 (24.4%)
   80+ 310 (5.9%) 84 (4.0%)
   Mean (SD) 65.1 (10.0) 62.9 (10.6)
Ethnicity   
   Arabic 3 (0.05%) 1 (0.05%)
   Asian 7 (0.13%) 6 (0.29%)
   Bangladeshi 1 (0.01%) 0
   Black-African 4 (0.08%) 1 (0.05%)
   Black-Caribbean 31 (0.59%) 8 (0.38%)
   Black-Other 1 (0.01%) 0
   Indian 16 (0.30%) 4 (0.19%)
   Jewish-Ashkenazi 12 (0.22%) 6 (0.29%)
   Pakistani 8 (0.15%) 0
   White 5,065 (96.1%) 1,947 (93.0%)
   Other/not specified 82 (1.6%) 121 (5.8%)
Reported asbestos exposure 807 (15.2%) 125 (6.0%)
Family history of lung cancer 750 (14.2%) 212 (10.1%)
Smoking habits   
   Never-smokers 307 (5.8%) 718 (34%)
   All smokers   
   Age first started smoking (SD) 16.5 (4.0) 17.9 (4.8%)
   Pack years in Smokers (SD) 47.2 (30.6) 30.4 (22.1%)
Histology of cancer   
Small cell (SCLC) 1,193 (22.6%)  
Non-small cell (NSCLC) 3,815 (72.4%)  
   Squamous 1,905 (49.9%)  
   Adenocarcinoma (including variants) 1,110 (29.1%)  
   Large cell 10 (0.3%)  
   Brochoalveolar 44 (1.2%)  
   Adenosquamous 11 (0.3%)  
   Neuroendocrine 20 (0.5%)  
   NSCLC unspecified 715 (18.7%)  
Sarcoma 5 (0.1%)  
Unclassified primary 256 (4.9%)  
Tumour stage at presentation, by histology   
   SCLC   
Limited 168 (50.4%)  
Extensive 165 (59.6%)  
   NSCLC   
I 151 (14.1%)  
II 140 (13.1%)  
III 457 (42.7%)  
IV 323 (30.2%)