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Table 1 Relative expression (medians) of HDAC genes in different groups of tumor and normal brain tissue.

From: Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas

 

Normal Brain

Astrocytoma grades I and II

Astrocytoma grade III

Glioblastoma

Class I

    

HDAC1

0.98

1.19

1.93

1.03

HDAC2

0.68

0.72

1.30

0.95

HDAC3

0.85

0.73

0.62

0.69

HDAC8

1.30

2.87

2.08

1.64

Class II

    

HDAC4

3.27

3.33

8.43

1.42

HDAC5

1.71

2.72

2.27

0.91

HDAC6

1.72

3.05

2.57

1.33

HDAC7

0.61

0.80

0.81

0.56

HDAC9a

30.74

24.46

30.51

11.49

HDAC9b

61.51

17.10

18.32

7.43

HDAC10

6.54

7.29

11.04

4.26

Class IV

    

HDAC11

3.67

3.30

3.05

1.02