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Table 2 Correlation between the clinicopathologic features and expression of CENP-H protein

From: Prognostic relevance of Centromere protein H expression in esophageal carcinoma

 

CENP-H

 

Characteristics

Low expression

High expression

P

Gender

   

   Male

67(51.9)

62(48.1)

0.013

   Female

31(73.8)

11(26.2)

 

Age(y)

   

   ≥ 60

58(56.3)

45(43.7)

0.747

   <60

40(58.8)

28(41.2)

 

Stage

   

   I

9(90.0)

1(10.0)

 

   II a

46(61.3)

29(38.7)

 

   II b

9 (64.3)

5(35.7)

0.023*

   III

30(47.6)

33(52.4)

 

   IV

4(44.4)

5(55.6)

 

Histological differentiation

   

   Well

30(54.5)

25(45.5)

 

   Moderate

42(58.3)

30(41.7)

0.637

   Poor

26(59.1)

18(40.9)

 

Tumor diameter

   

   ≥ 40 mm

37(51.4)

35(48.6)

0.184

   <40 mm

61(61.6)

38(38.4)

 

Depth of invasion

   

   Submucosa

8(66.7)

4(33.3)

0.212

   Muscularis propria

36(60.7)

22(39.3)

 

   Adventitia

54(53.8)

47(46.2)

 

pT classification

   

   T1~T2

41(69.5)

18(30.5)

0.019

   T3~T4

57(50.9)

55(49.1)

 

pN classification

   

   YES

38(49.4)

39(50.6)

0.057

   NO

60(63.8)

34(36.2)

 

pMetastasis

   

   YES

4(44.4)

5 (55.6)

0.426

   NO

94(58.0)

68 (42.0)

 
  1. *Stage I-II vs. III-IV