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Table 3 Association between ERG and TMPRSS2 SNP genotypes and TMPRSS2-ERG fusion status

From: Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer

    Fusion Status  
Gene SNP Genotype Negative Positive   P value
ERG rs1571704 GG 66 (84.6) 43 (89.6)   
   GT/TT 12 (15.4) 5 (10.4)   0.59
  rs1892570 CC 64 (81.0) 44 (91.7)   
   CT/TT 15 (19.0) 4 (8.3)   0.13
  rs2068967 GG 24 (30.4) 15 (31.3)   
   GA/AA 55 (69.6) 33 (68.7)   0.10
  rs2836370 TT 18 (22.5) 12 (25.5)   
   TC/CC 62 (77.5) 35 (74.5)   0.83
TMPRSS2 rs12329760 CC 53 (68.0) 26 (53.1)   
   CT/TT 25 (32.0) 23 (46.9)   0.13
    Negative Translocation Deletion  
ERG rs1571704 GG 66 (84.6) 18 (85.7) 25 (92.6)  
   GT/TT 12 (15.4) 3 (14.3) 2 (7.4) 0.66
  rs1892570 CC 64 (81.0) 19 (90.5) 25 (92.6)  
   CT/TT 15 (19.0) 2 (9.5) 2 (7.4) 0.33
  rs2068967 GG 24 (30.4) 9 (42.8) 6 (22.2)  
   GA/AA 55 (69.6) 12 (57.2) 21 (77.8) 0.31
  rs2836370 TT 18 (22.5) 5 (23.8) 7 (26.9)  
   TC/CC 62 (77.5) 16 (76.2) 19 (73.1) 0.91
TMPRSS2 rs12329760 CC 53 (68.0) 8 (38.1) 18 (64.3)  
   CT/TT 25 (32.0) 13 (61.9) 10 (35.7) 0.05
    Negative Single Multiple  
ERG rs1571704 GG 66 (84.6) 40 (93.0) 3 (60.0)  
   GT/TT 12 (15.4) 3 (7.0) 2 (40.0) 0.09
  rs1892570 CC 64 (81.0) 40 (93.0) 4 (80.0)  
   CT/TT 15 (19.0) 3 (7.0) 1 (20.0) 0.15
  rs2068967 GG 24 (30.4) 12 (27.9) 3 (60.0)  
   GA/AA 55 (69.6) 31 (72.1) 2 (40.0) 0.36
  rs2836370 TT 18 (22.5) 11 (26.2) 1 (20.0)  
   TC/CC 62 (77.5) 31 (73.8) 4 (80.0) 0.86
TMPRSS2 rs12329760 CC 53 (68.0) 25 (58.1) 1 (16.7)  
   CT/TT 25 (32.0) 18 (41.9) 5 (83.3) 0.03