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Figure 3 | BMC Cancer

Figure 3

From: A complex pattern of chemokine receptor expression is seen in osteosarcoma

Figure 3

Chemokine receptor expression pattern in the cellular context of osteosarcoma. (A) Immunostaining on human tonsil with a monoclonal AB directed against CCR7 (×200). (B) IgG2a isotype control for α-CCR7 on human tonsil. (C) Expression of CCR7 in atypical mononuclear cells and some giant cells between some filigree and arborizing osteoid (×400). (D) Goat serum isotype controle for α-CCR4 and α-CCR1 on osteosarcoma sections. (E) and (F) Polynuclear giant cells express CCR1 as well as atypical mononuclear cells (E) ×200 and F) ×400). (G) and H) Strong CCR4 expression on cells of the inner lining of intratumoral vessels ((G) ×200 and (H) ×400).

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