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Table 4 Multivariate Cox proportional hazard regression analysis of predicting factors for cancer-specific survival of metastatic prostate cancer patients (Stage D)

From: A genetic polymorphism of the osteoprotegerin gene is associated with an increased risk of advanced prostate cancer

  HR Cancer Specific Survival 95% CI P
PSA (ng/ml)    
   ≥260 1.984 0.756–5.210 0.164
   < 260    
hemoglobin (g/dl)    
   Abnormal (< 11.7) 2.632 1.140–6.077 0.023
   Normal (≥11.7)    
ALP (IU)    
   Abnormal (≥ 282) 2.557 0.994–6.574 0.051
   Normal (< 282)    
Grade    
   High 3.251 1.473–7.175 0.004
   Low/Intermediate    
OPG    
   T allele dosage 2.157 1.072–4.341 0.031
  1. Abbreviations: HR; hazard ratio, 95% CI; 95% confidence interval, PSA; prostate specific antigen, ALP, alkaline phosphatase, OPG; osteoprotegerin 950 T/C genotype
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