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Table 4 Multivariate Cox proportional hazard regression analysis of predicting factors for cancer-specific survival of metastatic prostate cancer patients (Stage D)

From: A genetic polymorphism of the osteoprotegerin gene is associated with an increased risk of advanced prostate cancer

 

HR

Cancer Specific Survival 95% CI

P

PSA (ng/ml)

   

   ≥260

1.984

0.756–5.210

0.164

   < 260

   

hemoglobin (g/dl)

   

   Abnormal (< 11.7)

2.632

1.140–6.077

0.023

   Normal (≥11.7)

   

ALP (IU)

   

   Abnormal (≥ 282)

2.557

0.994–6.574

0.051

   Normal (< 282)

   

Grade

   

   High

3.251

1.473–7.175

0.004

   Low/Intermediate

   

OPG

   

   T allele dosage

2.157

1.072–4.341

0.031

  1. Abbreviations: HR; hazard ratio, 95% CI; 95% confidence interval, PSA; prostate specific antigen, ALP, alkaline phosphatase, OPG; osteoprotegerin 950 T/C genotype
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BMC Cancer

ISSN: 1471-2407

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