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Table 3 Association between the clinical variables of patients with metastatic prostate cancer (Stage D) and the OPG 950T/C genotype

From: A genetic polymorphism of the osteoprotegerin gene is associated with an increased risk of advanced prostate cancer

  Osteoprotegerin 950T/C genotype  
  CC TC TT P 3
  n = 11 n = 39 n = 40  
Age1 74 (69–79) 75 (68–81) 72 (65–76) 0.375
Histological grade2     
Low/Intermediate 4 (9%) 18 (39%) 24 (52%) 0.641
High 7 (16%) 21 (48%) 16 (36%)  
Clinical variables at diagnosis1     
PSA (ng/ml) 199 (66.4–296) 257 (37.3–860) 116 (30.0–267) 0.270
Hemoglobin (g/dl) 12.8 (12.2–13.1) 12.7 (11.1–13.7) 13.2 (12.0–14.6) 0.194
ALP (IU/ml) 189 (175–468) 232 (177–360) 201 (138–343) 0.659
  1. 1Values represent the median (inter-quartile range).
  2. 2Values represent the number (%).
  3. 3Analysis of variance or chi-square test.
  4. Abbreviations: PSA; prostate specific antigen, ALP, alkaline phosphatase.
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