From: A high-throughput and sensitive method to measure Global DNA Methylation: Application in Lung Cancer
A | Â | Â | Â |
---|---|---|---|
Median GDMI of normal non-disease, normal disease and the paired tumors for different methyl-sensitive restriction enzymes. | |||
Sample Type | HinP1 I | HpyCH4 IV | Hpa II |
Normal Non-Disease | 0.163 | 0.304 | 0.293 |
Normal Disease | 0.197 | 0.368 | 0.321 |
Tumor | 0.216 | 0.427 | 0.379 |
B | Â | Â | Â |
Non-parametric tests of normal disease versus paired tumor, normal non-disease versus normal disease, and normal non-disease versus tumor for each of the methyl-sensitive restriction enzymes. | |||
Comparisons | HinP1 I | HpyCH4 IV | Hpa II |
Normal Disease vs Tumor | 0.068* | 0.201 | 0.064* |
Normal Non-Disease vs Normal Disease | 0.483 | 0.129 | 0.039** |
Normal Non-Disease vs Tumor | 0.005** | 0.054* | 0.004** |