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Table 4 Logistic regression assessing associations with persistence of abnormal smears following LLETZ: restricted to HIV-infected women (n = 196).

From: Predictors of persistent cytologic abnormalities after treatment of cervical intraepithelial neoplasia in Soweto, South Africa: a cohort study in a HIV high prevalence population

 

Univariate

Odds Ratio

(95% CI)

Multivariate

Odds Ratio

(95%CI)

p-value

CD4 category (cells/mm 3)

   

<200

Referent

Referent

-

200–499

0.45 (0.24 – 0.85)

0.4 (0.2–0.8)

0.017

≥500

0.2 (0.085 – 0.45)

0.1 (0.01–0.2)

0.000

Disease at excision margins

   

Margins not involved

Referent

Referent

-

Ectocervical margin positive

1.7 (0.93 – 3.3)

2.0 (0.9–4.6)

0.089

Endocervical margin positive

2.2 (0.8 – 5.8)

5.6 (1.3–24.8)

0.024

Both endo- and ectocervical margins involved

2.5 (0.86 – 7.1)

4.3 (0.9–19.2)

0.059

Histology of excised transformation zone

   

CIN1

Referent

Referent

-

CIN2

2.1 (0.8 – 5.3)

2.5 (0.8–7.8)

0.116

CIN3

2.5 (0.96 – 6.4)

3.8 (1.1–13.1)

0.037