| Univariate Odds Ratio (95% CI) | Multivariate Odds Ratio (95%CI) | p-value |
---|---|---|---|
HIV infection | 6.8 (4.3 – 10.7) | 8.2 (4.2–15.8) | <0.0001 |
Disease at excision margin of biopsy specimen | Â | Â | Â |
   No disease at the excision margins | Referent | Referent | - |
   Disease at the Ectocervical margin | 2.1 (1.4 – 3.2) | 2.2 (1.2–4.1) | 0.013 |
   Disease at the Endocervical margin | 0.96 (0.6 – 1.6) | 2.1 (0.9–5.5) | 0.09 |
   Both endocervical and ectocervical margins | 2.6 (1.4 – 5.0) | 10.7 (3.0–37.4) | <0.0001 |
Histology | Â | Â | Â |
   CIN1 | Referent | Referent | - |
   CIN2 | 2.0 (1.0 – 3.9) | 2.0 (0.8–5.1) | 0.17 |
   CIN3 | 1.6 (0.8 – 3.0) | 2.2 (0.8–6.0) | 0.12 |
   Micro-invasion | 0.4 (0.04 – 3.8) | 2.00 (0.04 – 96.7) | 0.73 |
Age > 35 years (median age) | 0.64 (0.5 – 0.9) | 0.58 (0.33 – 1.0) | 0.06 |