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Table 3 Logistic regression using data of all women whose HIV status was known showing associations with persistence of an abnormal smears following LLETZ (n = 295).

From: Predictors of persistent cytologic abnormalities after treatment of cervical intraepithelial neoplasia in Soweto, South Africa: a cohort study in a HIV high prevalence population

 

Univariate

Odds Ratio

(95% CI)

Multivariate

Odds Ratio

(95%CI)

p-value

HIV infection

6.8 (4.3 – 10.7)

8.2 (4.2–15.8)

<0.0001

Disease at excision margin of biopsy specimen

   

   No disease at the excision margins

Referent

Referent

-

   Disease at the Ectocervical margin

2.1 (1.4 – 3.2)

2.2 (1.2–4.1)

0.013

   Disease at the Endocervical margin

0.96 (0.6 – 1.6)

2.1 (0.9–5.5)

0.09

   Both endocervical and ectocervical margins

2.6 (1.4 – 5.0)

10.7 (3.0–37.4)

<0.0001

Histology

   

   CIN1

Referent

Referent

-

   CIN2

2.0 (1.0 – 3.9)

2.0 (0.8–5.1)

0.17

   CIN3

1.6 (0.8 – 3.0)

2.2 (0.8–6.0)

0.12

   Micro-invasion

0.4 (0.04 – 3.8)

2.00 (0.04 – 96.7)

0.73

Age > 35 years (median age)

0.64 (0.5 – 0.9)

0.58 (0.33 – 1.0)

0.06

  1. (n = 295).