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Figure 1 | BMC Cancer

Figure 1

From: ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo

Figure 1

Antiproliferative effects of ENMD-1198 on HCC cells. HUH-7 cells were incubated for 24 h with various concentrations of ENMD-1198 and MTT reading was performed thereafter. ENMD-1198 dose-dependently elicited significant antiproliferative effects on HCC cells with an IC50at 2.5 μM in both cell lines (data shown for HUH-7) (*P < 0.05). Bars represent mean ± SEM from three independent experiments. Bars: SEM.

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