Skip to main content

Table 3 Correlation of P53, BCL-2 and Cyclin D1 expression in KIT positive GISTs with clinicopathological features

From: P53 expression is significantly correlated with high risk of malignancy and epithelioid differentiation in GISTs. An immunohistochemical study of 104 cases

 

P53

BCL-2

Cyclin D1

Tumor size

0.01

0.408

0.243

Mitotic rate

0.013

0.207

0.625

Risk of malignancy (Fletcher [10])

<0.0001

0.36

0.776

Risk of malignancy (Miettinen [11])

0.001

0.196

0.512

Nuclear atypia

0.02

0.676

0.38

Proliferative activity (Ki67)

0.01

0.794

0.352

Histological subtype

0.002

0.391

0.782

Tumor site

0.099

0.118

0.573

  1. Bold: significant probability