Skip to main content

Table 3 Correlation of P53, BCL-2 and Cyclin D1 expression in KIT positive GISTs with clinicopathological features

From: P53 expression is significantly correlated with high risk of malignancy and epithelioid differentiation in GISTs. An immunohistochemical study of 104 cases

  P53 BCL-2 Cyclin D1
Tumor size 0.01 0.408 0.243
Mitotic rate 0.013 0.207 0.625
Risk of malignancy (Fletcher [10]) <0.0001 0.36 0.776
Risk of malignancy (Miettinen [11]) 0.001 0.196 0.512
Nuclear atypia 0.02 0.676 0.38
Proliferative activity (Ki67) 0.01 0.794 0.352
Histological subtype 0.002 0.391 0.782
Tumor site 0.099 0.118 0.573
  1. Bold: significant probability