Figure 5
From: The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells
Requirement of the C-terminus of BCL9 for Wnt-induced transcription. Transcript levels of c-MYC and AXIN2, as measured by RT-qPCR, in Wnt-induced HEK 293 cells (as in Fig. 3) after overexpression of wt or mutant (A) FLAG-BCL9 or (B) FLAG-BCL9-2. Statistical significance (p < 0.01) relative to Wnt-stimulated control cells (set arbitrarily to 100%) is indicated by asterisks above bars.