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Table 4 The areas under curve for proteolytic enzymes, CEA and CA 19-9 according to ROC curves.

From: Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer

Variable

AUC

Lower limit

Upper limit

PAI-1

0.9385

0.9025

0.9744

CATB

0.8665

0.7934

0.9397

uPA

0.7143

0.6091

0.8196

CATL

0.6173

0.5158

0.7188

CA 19-9

0.4990

0.3937

0.6043

CEA

0.4748

0.3690

0.5807

  1. Determination of areas under curve for cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 according to ROC curves allowing to evaluate their accuracy and different discriminative power
  2. Abbreviations: AUC: area under curve; CATB: cathepsin B; CATL: cathepsin L; uPA: urokinase-type plasminogen activator, PAI-1: plasminogen activator inhibitor type-1; CEA: carcinoembryonic antigen; CA 19-9: carbohydrate antigen 19-9; ROC: receiver operating characteristics
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BMC Cancer

ISSN: 1471-2407

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