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Table 4 The areas under curve for proteolytic enzymes, CEA and CA 19-9 according to ROC curves.

From: Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer

Variable AUC Lower limit Upper limit
PAI-1 0.9385 0.9025 0.9744
CATB 0.8665 0.7934 0.9397
uPA 0.7143 0.6091 0.8196
CATL 0.6173 0.5158 0.7188
CA 19-9 0.4990 0.3937 0.6043
CEA 0.4748 0.3690 0.5807
  1. Determination of areas under curve for cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 according to ROC curves allowing to evaluate their accuracy and different discriminative power
  2. Abbreviations: AUC: area under curve; CATB: cathepsin B; CATL: cathepsin L; uPA: urokinase-type plasminogen activator, PAI-1: plasminogen activator inhibitor type-1; CEA: carcinoembryonic antigen; CA 19-9: carbohydrate antigen 19-9; ROC: receiver operating characteristics