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Table 2 Up-regulation of EGFR ligands in RasV12- and Ras EDM-expressing HME16C

From: TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation

Gene V12 S35 G37 C40
epiregulin 2.6 (7.0) 1.9 (1.0) 1.8 (2.4) 1.2 (1.3)
TGFa 3.5 (3.4) 2.9 (1.3) -1.1 (-1.4) 1.9 (-1.1)
amphiregulin 1.4 (2.4) 2.9 (1.0) 2.3 (1.7) 2.2 (1.0)
  1. Fold up-regulation of the EGFR ligands epiregulin, transforming growth factor alpha (TGFa), and epiregulin in RasV12- and Ras EDM-expressing HME16C as determined by real-time RT-PCR quantification (boldface) and cDNA microarray analysis (in parentheses).