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Table 2 Up-regulation of EGFR ligands in RasV12- and Ras EDM-expressing HME16C

From: TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation

Gene

V12

S35

G37

C40

epiregulin

2.6 (7.0)

1.9 (1.0)

1.8 (2.4)

1.2 (1.3)

TGFa

3.5 (3.4)

2.9 (1.3)

-1.1 (-1.4)

1.9 (-1.1)

amphiregulin

1.4 (2.4)

2.9 (1.0)

2.3 (1.7)

2.2 (1.0)

  1. Fold up-regulation of the EGFR ligands epiregulin, transforming growth factor alpha (TGFa), and epiregulin in RasV12- and Ras EDM-expressing HME16C as determined by real-time RT-PCR quantification (boldface) and cDNA microarray analysis (in parentheses).
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BMC Cancer

ISSN: 1471-2407

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