Figure 4From: Clinical implications of thymidylate synthetase, dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activity levels in colorectal carcinoma following radical resection and administration of adjuvant 5-FU chemotherapy Disease free survival for patients with high OPRT activity and low OPRT activity. The 5-year disease-free survival rates for high and low OPRT activity were 75% and 28%, respectively. The difference in survival was statistically significant. (P < 0.05)Back to article page